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When the President got into an accident, Shirotani Tadaomi met Kurose. On their very first meeting, Kurose could tell right away that Shirotani is Mysophobic and said that it’s pretty bad while suggesting it would be better to consult a doctor about it. Shirotani was left perturbed by the encounter. Who is Kurose? And how was he able to tell Shirotani’s condition?
Corporate secretary Shirotani suffers from obsessive-compulsive disorder. One day he meets Kurose, a therapist who offers to take him through a ten-step program to cure him of his compulsion. As the two go through each of the ten steps, Shirotani 's attraction to his counselor grows.
On a whim, high school third-year Yuzuru Shino asks out first-year Toji Seryo, who is notorious for being a weeklong lover—he’ll date the first girl to ask him out Monday morning and then promptly dump her by the following Monday! The boys start dating, and by Tuesday, the first inklings of attraction hit. Can Seryo put words to his feelings before Monday comes, or are old dating habits too hard to break?
Youichi's life at university is going just fine. He isn't having any trouble with his classes, he has plenty of friends, and even a cute girlfriend named Minami. Then the day comes where he meets Misaki. Misaki is a reserved, stand offish fellow but for some reason, Youichi can't seem to get him out of his mind. In fact, he can't seem to stay away. When he lands a job working in the lab with Misaki, it seems more than just the flowers are about to bloom. But will they recognise their emotions for what they are, and have the courage to accept it?
The successor of the Tsujimura clinic, Motoharu has always held his childhood friend, Hazumi Akira, close to his heart. He confessed to Akira and then was rejected. Even so, he still entered the same university and same department as Akira. Ever since the confession, the two have been distancing each other, but Akira suggested that they make up and for the first time in a while, they walk home together. But on the way back, Akira suddenly kisses Motoharu, causing Motoharu’s hope to grow. However, the next day, Akira tells him to forget it?, causing Motoharu to blame Akira... Includes Hana no Migoro ni A short sequel for Hana No Mizo Shiru portraying Misaki and Youichi’s life after the events of the main plot.
A short sequel for Hana No Mizo Shiru portraying Misaki and Youichi's life after the events of the main plot.